In the United States, $83 billion is spent annually by the pharmaceutical industry to develop new drugs. The R&D stage contributes $26B in annual costs at a net $474M per drug that reaches FDA approval. The process to develop a single drug generally takes 11-16 years. In the semiconductor industry, the Intel mantra is "fail fast" -- and in a startup, the goal is to find a technology that disrupts a market. The Children's Cancer Therapy Development Institute (cc-tdi.org) seeks to make the nonprofitable pursuit of curative drugs for rare childhood cancers and adult sarcomas more feasible through the introduction of disruptive, innovative engineering approaches more typical of the Oregon Silicon Forest.